ED Medication Comparison Tool
Select your preferences to compare ED medications:
| Drug | Onset (min) | Duration (hr) | Side Effects |
|---|---|---|---|
| Sildigra (Viagra) | 30-60 | 4-6 | Moderate |
| Cialis | 30-120 | Up to 36 | Lower |
| Levitra | 15-30 | 4-5 | Moderate |
| Stendra | 10-15 | 6-12 | Low |
Sildigra is a prescription medication that contains sildenafil citrate, the active ingredient in the original brand Viagra. It belongs to the PDE5 inhibitor class and is used to treat erectile dysfunction (ED) by increasing blood flow to the penis.
How Sildigra Works
When a man is sexually aroused, nitric oxide is released in the penile tissue. This triggers the production of cyclic guanosine monophosphate (cGMP), which relaxes smooth muscle and allows blood to fill the corpora cavernosa. Sildenafil inhibits the enzyme phosphodiesterase type 5 (PDE5), preventing the breakdown of cGMP. The result is a sustained erection that can last for several hours.
Key Attributes of Sildigra
- Generic name: Sildenafil citrate
- Typical dose: 25mg, 50mg, or 100mg taken about an hour before sexual activity
- Onset: 30-60minutes
- Duration: 4-6hours
- FDA approval year: 1998 (original brand)
- Metabolism: Primarily via CYP3A4 in the liver
Common Alternatives to Sildigra
Four other PDE5 inhibitors dominate the market. Each has its own dosing schedule, onset time and side‑effect profile.
Viagra is the brand‑name version of sildenafil, approved by the FDA in 1998. It shares the same active ingredient as Sildigra, but the branding and price can differ.
Cialis contains tadalafil, a longer‑acting PDE5 inhibitor. Its effects can last up to 36hours, earning it the nickname “the weekend pill”.
Levitra uses vardenafil, another sildenafil‑type compound. It tends to have a slightly faster onset (15-30minutes) but a similar duration of 4-5hours.
Stendra is the brand name for avanafil, a newer PDE5 inhibitor. It can work in as little as 10minutes and has fewer visual side effects for many users.
Side‑Effect Profile Across the Class
All PDE5 inhibitors share a core set of side effects because they act on the same enzyme. The most frequently reported are:
- Headache
- Flushing
- Indigestion
- Nasal congestion
- Visual disturbances (more common with sildenafil)
Serious events such as sudden hearing loss or priapism are rare but require immediate medical attention.
Choosing the Right ED Medication
When deciding between Sildigra and its alternatives, consider three practical factors: timing, duration, and personal tolerance.
- Timing: If you need an option that works within 15minutes, avanafil (Stendra) is the clear choice.
- Duration: For spontaneous plans that may stretch over a day, tadalafil (Cialis) offers the longest window.
- Tolerance: Some men report milder visual changes with tadalafil or vardenafil compared to sildenafil.
Insurance coverage can also sway the decision. Generic sildenafil (Sildigra) is often the most affordable, while brand‑name options may be covered by specific health plans.
Safety Considerations and Contra‑indications
All PDE5 inhibitors are contraindicated with nitrates (e.g., nitroglycerin) because the combination can cause a dangerous drop in blood pressure. Patients with severe cardiovascular disease, recent stroke, or uncontrolled hypertension should discuss risks with a doctor before starting any ED drug.
Kidney or liver impairment can affect drug metabolism. Tadalafil, for instance, is eliminated more slowly in patients with severe hepatic disease, requiring dose adjustments.
Buying Sildigra Safely Online
Online pharmacies have lowered the barrier to access, but they also introduce counterfeit risk. Look for these hallmarks of a reputable source:
- Verified pharmacy accreditation (e.g., LegitScript, PharmacyChecker)
- Clear prescription requirement - reputable sites never sell ED meds without one
- Transparent pricing and shipping policies
- Contact information and a physical address in the same country
Purchasing from a trusted Australian online pharmacy ensures the product meets the Therapeutic Goods Administration (TGA) standards for safety and efficacy.
Comparison Table: Sildigra vs Major Alternatives
| Drug | Generic Name | Typical Dose | Onset | Duration | FDA Approval |
|---|---|---|---|---|---|
| Sildigra (Viagra) | Sildenafil citrate | 50mg | 30‑60min | 4‑6hr | 1998 |
| Cialis | Tadalafil | 20mg | 30‑120min | Up to 36hr | 2003 |
| Levitra | Vardenafil | 10mg | 15‑30min | 4‑5hr | 2003 |
| Stendra | Avanafil | 100mg | 10‑15min | 6‑12hr | 2012 |
Related Concepts to Explore
Understanding the broader context helps you make smarter choices. Below are topics that naturally follow a deep dive into Sildigra:
- Erectile dysfunction a condition affecting up to 30% of men over 40
- PDE5 inhibitor class includes sildenafil, tadalafil, vardenafil, and avanafil
- Cardiovascular safety research shows most men with stable heart disease can safely use PDE5 inhibitors
- Generic vs brand medication price, bioequivalence and patient perception differences
- Online pharmacy regulation role of agencies like TGA and FTC in protecting consumers
Next Steps for Readers
If you’re ready to try Sildigra or another ED medication, follow this quick checklist:
- Schedule a telehealth or in‑person appointment to get a valid prescription.
- Compare prices between reputable Australian online pharmacies and local dispensaries.
- Review the side‑effect profile and note any personal health conditions that could interact.
- Start with the lowest effective dose (often 25mg for sildenafil) and adjust as needed.
- Keep a short diary of onset time, duration and any adverse reactions to discuss with your doctor.
Frequently Asked Questions
Is Sildigra the same as Viagra?
Yes. Sildigra contains the same active ingredient-sildenafil citrate-as the brand‑name Viagra. The main differences are price, packaging and the fact that Sildigra is marketed as a generic.
Can I take Sildigra with alcohol?
Moderate alcohol consumption usually doesn’t interfere with the drug’s effectiveness, but heavy drinking can lower blood pressure and increase the risk of side effects like dizziness.
How does tadalafil (Cialis) differ from sildenafil?
Tadalafil has a much longer half‑life, giving a therapeutic window up to 36hours, whereas sildenafil’s effect typically wears off after 4‑6hours. Tadalafil also tends to cause fewer visual disturbances.
Are there any foods that affect Sildigra’s absorption?
A high‑fat meal can delay sildenafil’s onset by up to 60minutes. If timing is critical, take the tablet on an empty stomach or after a light meal.
What should I do if I experience a painful erection lasting more than 4 hours?
Seek emergency medical care immediately. A prolonged erection (priapism) can damage penile tissue and requires prompt treatment.
Is a prescription required for Sildigra in Australia?
Yes. Australian law mandates a valid prescription for all PDE5 inhibitors, including generic sildenafil. Online pharmacies must verify the prescription before dispensing.
Can women use Sildigra?
Sildenafil is approved for pulmonary arterial hypertension in both sexes, but it is not approved for treating female sexual dysfunction. Off‑label use should only occur under specialist supervision.
KISHORE KANKIPATI
September 25, 2025 AT 19:39Reading through the table, it’s clear that each drug paints a different picture for the bedroom marathon. Stendra flashes the fastest green light, while Cialis spreads the party over a whole day. If you’re chasing a balance between speed and staying power, the middle ground of Viagra feels like a safe middle‑ground. Ultimately, the best pick matches your own rhythm, not the label’s hype.