What is Poxet (Dapoxetine) and how does it work?
Poxet is the brand name for dapoxetine, a short-acting selective serotonin reuptake inhibitor (SSRI) approved specifically for treating premature ejaculation (PE) in men aged 18 to 64. Unlike other SSRIs used for depression, which take weeks to build up in your system, dapoxetine is taken 1 to 3 hours before sexual activity. It works by increasing serotonin levels in the brain, which helps delay ejaculation.
Studies show that men using dapoxetine typically report an increase in intravaginal ejaculatory latency time (IELT) from under a minute to over 2 to 3 minutes on average. That might not sound like much, but for many, it’s the difference between frustration and confidence.
Why do men look for alternatives to Poxet?
Even though Poxet works for many, it’s not the right fit for everyone. Some men experience side effects like nausea, dizziness, headaches, or a feeling of lightheadedness after taking it. Others find the timing too restrictive - having to plan sex around a pill isn’t always practical. A few report reduced libido or difficulty maintaining an erection. And for some, the cost adds up over time, especially if they’re paying out-of-pocket.
That’s why many start asking: Are there other options? Can I get similar results without the side effects? Is there something more natural or less expensive?
Top alternatives to Poxet (Dapoxetine)
There are several other treatments for premature ejaculation, each with different mechanisms, pros, and cons. Here are the most commonly used alternatives.
1. Other SSRIs: Paroxetine, Sertraline, Fluoxetine
These are antidepressants that also delay ejaculation - but they’re not designed for on-demand use. You have to take them daily for several weeks before noticing any effect. That’s a big difference from Poxet, which works in a few hours.
Paroxetine tends to be the most effective for PE, with studies showing IELT increases of up to 4 to 5 minutes after 4 to 6 weeks. But daily use brings risks: weight gain, sexual dysfunction (including delayed orgasm in partners), and withdrawal symptoms if you stop suddenly. Not ideal if you want flexibility.
2. Topical anesthetics: Lidocaine or Prilocaine sprays and creams
These numbing agents reduce penile sensitivity, helping men last longer. They’re applied 10 to 15 minutes before sex and washed off before intercourse to avoid numbing your partner.
Advantages: No systemic side effects, works immediately, no prescription needed in many places. Disadvantages: Can reduce sensation too much, messy to apply, risk of partner numbness if not cleaned properly. Some men say it kills the mood.
Brands like Promescent and Stud 100 are widely available. A 2023 review in the Journal of Sexual Medicine found topical anesthetics improved IELT by 1.5 to 3 minutes on average - similar to dapoxetine, but with fewer internal side effects.
3. Behavioral techniques: Start-stop and squeeze method
These are non-medical approaches that train your body to recognize and control the point of no return. The start-stop method involves pausing stimulation when you feel close to ejaculating, then resuming after the urge fades. The squeeze method involves squeezing the head of the penis to reduce arousal.
Research from the University of California shows that after 8 to 12 weeks of consistent practice, over 70% of men saw significant improvement in control. No pills, no side effects, no cost - but it takes discipline and patience. Works best when combined with counseling or partner support.
4. Phosphodiesterase-5 inhibitors: Sildenafil (Viagra), Tadalafil (Cialis)
These are erectile dysfunction drugs, but they’re sometimes used off-label for PE, especially if erectile issues are also present. The theory is that better erections lead to more confidence, which reduces performance anxiety - a major trigger for PE.
A 2022 clinical trial found that men using tadalafil daily (2.5 mg) alongside behavioral therapy improved IELT by 2.8 minutes, compared to 2.1 minutes with dapoxetine alone. The combo worked better than either treatment by itself.
Downside: These drugs don’t directly delay ejaculation. They help indirectly. And they’re not safe for men with heart conditions or those taking nitrates.
5. Natural supplements: L-arginine, Panax ginseng, Zingiber officinale (ginger)
Some men turn to herbal or supplement-based options. L-arginine, an amino acid, may improve blood flow and nitric oxide production, potentially helping with control. Ginseng has been linked to improved sexual function in small studies. Ginger is sometimes used for its anti-inflammatory and circulation-boosting effects.
But here’s the catch: There’s very little high-quality evidence. Most studies are small, poorly controlled, or funded by supplement companies. A 2024 meta-analysis in Complementary Therapies in Medicine concluded that none of these supplements have proven efficacy for PE beyond placebo. They’re not regulated like drugs, so dosing and purity vary widely.
Comparison table: Poxet vs. Alternatives
| Treatment | How It Works | Time to Effect | Duration of Effect | Common Side Effects | Prescription Needed? |
|---|---|---|---|---|---|
| Poxet (Dapoxetine) | SSRI that increases serotonin | 1-3 hours | 4-6 hours | Nausea, dizziness, headache | Yes |
| Paroxetine (daily SSRI) | SSRI with cumulative effect | 2-6 weeks | 24/7 | Weight gain, low libido, fatigue | Yes |
| Lidocaine cream/spray | Local numbing | 10-15 minutes | 1-2 hours | Reduced sensation, partner numbness | No |
| Start-stop technique | Behavioral training | 8-12 weeks | Long-term | None | No |
| Tadalafil (daily low dose) | Improves erection quality | Daily use, 1-2 weeks | 24-36 hours | Headache, flushing, back pain | Yes |
| L-arginine / Ginseng | Unproven mechanisms | Unclear | Unclear | Mild GI upset | No |
Which option is right for you?
The best choice depends on your goals, lifestyle, and health.
- If you want fast, reliable results and don’t mind taking a pill before sex, Poxet is still the most studied and effective single-agent option.
- If you’re uncomfortable with pills or get nauseous easily, try a topical anesthetic - just be careful with application.
- If you’re dealing with anxiety or performance pressure, combine behavioral techniques with counseling. It’s the most sustainable solution.
- If you also struggle with erections, talk to your doctor about combining tadalafil with Poxet or therapy.
- Avoid unregulated supplements unless you’re using them as a complement to proven methods - don’t expect miracles.
What to avoid
There are a lot of scams out there. Avoid products marketed as "miracle cures" for PE - especially those sold online without a prescription. Many contain hidden drugs like sildenafil or dapoxetine at unregulated doses, which can be dangerous if you have heart issues or take other medications.
Also, don’t rely on YouTube videos or forums for medical advice. What works for one person might not work for you. Always consult a doctor before starting any new treatment, even if it’s "over-the-counter."
When to see a doctor
See a healthcare provider if:
- PE has been happening for more than 6 months
- You’re also having trouble getting or keeping an erection
- It’s causing stress, anxiety, or relationship problems
- You’ve tried OTC products with no results
- You have other health conditions like diabetes, heart disease, or depression
A doctor can rule out underlying causes and help you choose a safe, effective plan. You don’t have to live with this alone.
Final thoughts
Poxet isn’t the only solution for premature ejaculation - but it’s one of the few with solid clinical backing. The real key is matching the treatment to your needs. Some men need a pill. Others need a technique. Some need both. And many benefit from simply talking about it - with a partner or a professional.
There’s no shame in seeking help. Premature ejaculation is common - affecting up to 30% of men at some point. The fact that you’re looking for answers means you’re already on the right path.
Is Poxet better than other SSRIs for premature ejaculation?
Yes, for on-demand use. Other SSRIs like paroxetine or sertraline require daily use and take weeks to work. Poxet (dapoxetine) is designed specifically for PE and works within hours. It’s the only SSRI approved for this use in many countries, including Australia and the EU. Other SSRIs are used off-label and carry higher risks of long-term side effects.
Can I take Poxet with Viagra?
Some men do take both, but only under medical supervision. Poxet and sildenafil (Viagra) work differently - one delays ejaculation, the other improves erections. Combining them can be effective for men with both PE and ED. But both can lower blood pressure, so there’s a risk of dizziness or fainting. Never combine them without talking to your doctor first.
Are topical sprays as effective as Poxet?
They can be. Studies show topical anesthetics like lidocaine spray improve IELT by about 1.5 to 3 minutes, similar to dapoxetine. But they don’t work the same way - they reduce sensation, while Poxet affects brain chemistry. Some men prefer sprays because they avoid systemic side effects. Others find them messy or too numbing. Effectiveness varies by person.
How long does it take for behavioral techniques to work?
Most men see improvement after 6 to 8 weeks of consistent practice. The start-stop and squeeze methods require regular training - ideally 3 to 5 times per week. It’s not a quick fix, but the results last longer than medication. Many men report better control even after stopping the exercises. Combining them with therapy increases success rates.
Is Poxet available over the counter?
No. Poxet (dapoxetine) is a prescription-only medication in Australia and most other countries. You can’t legally buy it without a doctor’s prescription. Be cautious of online sellers offering it without a prescription - many sell counterfeit or unsafe versions. Always get it from a licensed pharmacy with a valid prescription.
Can lifestyle changes help with premature ejaculation?
Yes. Reducing stress, improving sleep, quitting smoking, limiting alcohol, and exercising regularly can all help. Performance anxiety is a major trigger for PE, and physical fitness improves overall sexual confidence. While these won’t replace medical treatments, they support them. Many men find that combining healthy habits with behavioral therapy gives the best long-term results.
Next steps
If you’re considering treatment for premature ejaculation, start by tracking your symptoms. How often does it happen? Does it affect your confidence or relationship? Write it down. Then schedule a chat with your doctor. Bring your list of questions and any products you’ve tried. You don’t need to have all the answers - just the willingness to look for them.
There are options. You’re not alone. And with the right approach, lasting improvement is possible.