What is Poxet (Dapoxetine) and how does it work?
Poxet is the brand name for dapoxetine, a short-acting selective serotonin reuptake inhibitor (SSRI) approved specifically for treating premature ejaculation (PE) in men aged 18 to 64. Unlike other SSRIs used for depression, which take weeks to build up in your system, dapoxetine is taken 1 to 3 hours before sexual activity. It works by increasing serotonin levels in the brain, which helps delay ejaculation.
Studies show that men using dapoxetine typically report an increase in intravaginal ejaculatory latency time (IELT) from under a minute to over 2 to 3 minutes on average. That might not sound like much, but for many, it’s the difference between frustration and confidence.
Why do men look for alternatives to Poxet?
Even though Poxet works for many, it’s not the right fit for everyone. Some men experience side effects like nausea, dizziness, headaches, or a feeling of lightheadedness after taking it. Others find the timing too restrictive - having to plan sex around a pill isn’t always practical. A few report reduced libido or difficulty maintaining an erection. And for some, the cost adds up over time, especially if they’re paying out-of-pocket.
That’s why many start asking: Are there other options? Can I get similar results without the side effects? Is there something more natural or less expensive?
Top alternatives to Poxet (Dapoxetine)
There are several other treatments for premature ejaculation, each with different mechanisms, pros, and cons. Here are the most commonly used alternatives.
1. Other SSRIs: Paroxetine, Sertraline, Fluoxetine
These are antidepressants that also delay ejaculation - but they’re not designed for on-demand use. You have to take them daily for several weeks before noticing any effect. That’s a big difference from Poxet, which works in a few hours.
Paroxetine tends to be the most effective for PE, with studies showing IELT increases of up to 4 to 5 minutes after 4 to 6 weeks. But daily use brings risks: weight gain, sexual dysfunction (including delayed orgasm in partners), and withdrawal symptoms if you stop suddenly. Not ideal if you want flexibility.
2. Topical anesthetics: Lidocaine or Prilocaine sprays and creams
These numbing agents reduce penile sensitivity, helping men last longer. They’re applied 10 to 15 minutes before sex and washed off before intercourse to avoid numbing your partner.
Advantages: No systemic side effects, works immediately, no prescription needed in many places. Disadvantages: Can reduce sensation too much, messy to apply, risk of partner numbness if not cleaned properly. Some men say it kills the mood.
Brands like Promescent and Stud 100 are widely available. A 2023 review in the Journal of Sexual Medicine found topical anesthetics improved IELT by 1.5 to 3 minutes on average - similar to dapoxetine, but with fewer internal side effects.
3. Behavioral techniques: Start-stop and squeeze method
These are non-medical approaches that train your body to recognize and control the point of no return. The start-stop method involves pausing stimulation when you feel close to ejaculating, then resuming after the urge fades. The squeeze method involves squeezing the head of the penis to reduce arousal.
Research from the University of California shows that after 8 to 12 weeks of consistent practice, over 70% of men saw significant improvement in control. No pills, no side effects, no cost - but it takes discipline and patience. Works best when combined with counseling or partner support.
4. Phosphodiesterase-5 inhibitors: Sildenafil (Viagra), Tadalafil (Cialis)
These are erectile dysfunction drugs, but they’re sometimes used off-label for PE, especially if erectile issues are also present. The theory is that better erections lead to more confidence, which reduces performance anxiety - a major trigger for PE.
A 2022 clinical trial found that men using tadalafil daily (2.5 mg) alongside behavioral therapy improved IELT by 2.8 minutes, compared to 2.1 minutes with dapoxetine alone. The combo worked better than either treatment by itself.
Downside: These drugs don’t directly delay ejaculation. They help indirectly. And they’re not safe for men with heart conditions or those taking nitrates.
5. Natural supplements: L-arginine, Panax ginseng, Zingiber officinale (ginger)
Some men turn to herbal or supplement-based options. L-arginine, an amino acid, may improve blood flow and nitric oxide production, potentially helping with control. Ginseng has been linked to improved sexual function in small studies. Ginger is sometimes used for its anti-inflammatory and circulation-boosting effects.
But here’s the catch: There’s very little high-quality evidence. Most studies are small, poorly controlled, or funded by supplement companies. A 2024 meta-analysis in Complementary Therapies in Medicine concluded that none of these supplements have proven efficacy for PE beyond placebo. They’re not regulated like drugs, so dosing and purity vary widely.
Comparison table: Poxet vs. Alternatives
| Treatment | How It Works | Time to Effect | Duration of Effect | Common Side Effects | Prescription Needed? |
|---|---|---|---|---|---|
| Poxet (Dapoxetine) | SSRI that increases serotonin | 1-3 hours | 4-6 hours | Nausea, dizziness, headache | Yes |
| Paroxetine (daily SSRI) | SSRI with cumulative effect | 2-6 weeks | 24/7 | Weight gain, low libido, fatigue | Yes |
| Lidocaine cream/spray | Local numbing | 10-15 minutes | 1-2 hours | Reduced sensation, partner numbness | No |
| Start-stop technique | Behavioral training | 8-12 weeks | Long-term | None | No |
| Tadalafil (daily low dose) | Improves erection quality | Daily use, 1-2 weeks | 24-36 hours | Headache, flushing, back pain | Yes |
| L-arginine / Ginseng | Unproven mechanisms | Unclear | Unclear | Mild GI upset | No |
Which option is right for you?
The best choice depends on your goals, lifestyle, and health.
- If you want fast, reliable results and don’t mind taking a pill before sex, Poxet is still the most studied and effective single-agent option.
- If you’re uncomfortable with pills or get nauseous easily, try a topical anesthetic - just be careful with application.
- If you’re dealing with anxiety or performance pressure, combine behavioral techniques with counseling. It’s the most sustainable solution.
- If you also struggle with erections, talk to your doctor about combining tadalafil with Poxet or therapy.
- Avoid unregulated supplements unless you’re using them as a complement to proven methods - don’t expect miracles.
What to avoid
There are a lot of scams out there. Avoid products marketed as "miracle cures" for PE - especially those sold online without a prescription. Many contain hidden drugs like sildenafil or dapoxetine at unregulated doses, which can be dangerous if you have heart issues or take other medications.
Also, don’t rely on YouTube videos or forums for medical advice. What works for one person might not work for you. Always consult a doctor before starting any new treatment, even if it’s "over-the-counter."
When to see a doctor
See a healthcare provider if:
- PE has been happening for more than 6 months
- You’re also having trouble getting or keeping an erection
- It’s causing stress, anxiety, or relationship problems
- You’ve tried OTC products with no results
- You have other health conditions like diabetes, heart disease, or depression
A doctor can rule out underlying causes and help you choose a safe, effective plan. You don’t have to live with this alone.
Final thoughts
Poxet isn’t the only solution for premature ejaculation - but it’s one of the few with solid clinical backing. The real key is matching the treatment to your needs. Some men need a pill. Others need a technique. Some need both. And many benefit from simply talking about it - with a partner or a professional.
There’s no shame in seeking help. Premature ejaculation is common - affecting up to 30% of men at some point. The fact that you’re looking for answers means you’re already on the right path.
Is Poxet better than other SSRIs for premature ejaculation?
Yes, for on-demand use. Other SSRIs like paroxetine or sertraline require daily use and take weeks to work. Poxet (dapoxetine) is designed specifically for PE and works within hours. It’s the only SSRI approved for this use in many countries, including Australia and the EU. Other SSRIs are used off-label and carry higher risks of long-term side effects.
Can I take Poxet with Viagra?
Some men do take both, but only under medical supervision. Poxet and sildenafil (Viagra) work differently - one delays ejaculation, the other improves erections. Combining them can be effective for men with both PE and ED. But both can lower blood pressure, so there’s a risk of dizziness or fainting. Never combine them without talking to your doctor first.
Are topical sprays as effective as Poxet?
They can be. Studies show topical anesthetics like lidocaine spray improve IELT by about 1.5 to 3 minutes, similar to dapoxetine. But they don’t work the same way - they reduce sensation, while Poxet affects brain chemistry. Some men prefer sprays because they avoid systemic side effects. Others find them messy or too numbing. Effectiveness varies by person.
How long does it take for behavioral techniques to work?
Most men see improvement after 6 to 8 weeks of consistent practice. The start-stop and squeeze methods require regular training - ideally 3 to 5 times per week. It’s not a quick fix, but the results last longer than medication. Many men report better control even after stopping the exercises. Combining them with therapy increases success rates.
Is Poxet available over the counter?
No. Poxet (dapoxetine) is a prescription-only medication in Australia and most other countries. You can’t legally buy it without a doctor’s prescription. Be cautious of online sellers offering it without a prescription - many sell counterfeit or unsafe versions. Always get it from a licensed pharmacy with a valid prescription.
Can lifestyle changes help with premature ejaculation?
Yes. Reducing stress, improving sleep, quitting smoking, limiting alcohol, and exercising regularly can all help. Performance anxiety is a major trigger for PE, and physical fitness improves overall sexual confidence. While these won’t replace medical treatments, they support them. Many men find that combining healthy habits with behavioral therapy gives the best long-term results.
Next steps
If you’re considering treatment for premature ejaculation, start by tracking your symptoms. How often does it happen? Does it affect your confidence or relationship? Write it down. Then schedule a chat with your doctor. Bring your list of questions and any products you’ve tried. You don’t need to have all the answers - just the willingness to look for them.
There are options. You’re not alone. And with the right approach, lasting improvement is possible.
Lenard Trevino
October 31, 2025 AT 15:01Okay so let me tell you about my buddy Dave-he tried Poxet, thought it was magic, then one night he took it with a couple beers and ended up face-planting into the couch while his girlfriend screamed 'ARE YOU DEAD?' I mean, yeah, it works-but it’s like giving a toddler a chainsaw and saying 'be careful.' The dizziness? The nausea? The feeling your brain is made of wet cardboard? Worth it? Only if you're okay with your sex life being scheduled like a dentist appointment.
And don't even get me started on the 'natural remedies.' L-arginine? I tried that for three weeks. Ate a bunch of nuts, drank green tea, and still came faster than a Netflix autoplay. Meanwhile, my dog knows when I'm about to climax because he starts barking. That's my 'behavioral technique' now: train the dog to interrupt you. Works better than anything.
Topical sprays? Sure, they numb you, but then your partner feels like they're kissing a statue. I used Promescent once and my girlfriend asked if I'd been dipped in ice. I said 'no, just science.' She said 'science is a cold bitch.' Fair.
And the SSRIs? Daily pills? No thanks. I don't want my mood regulated by Big Pharma while my libido gets locked in a basement. I want to feel alive, not chemically sedated. I'd rather just… not have sex than be on antidepressants just to last 90 seconds.
But here's the thing-behavioral stuff? Start-stop? Squeeze? Sounds ridiculous until you actually do it. I spent six weeks practicing like I was training for the Olympics. Now I can last 15 minutes if I want to. No pills. No sprays. Just me, my breath, and a whole lot of patience. It's not sexy, but it's real.
And if you're thinking about combining Poxet with Viagra? Don't. Just… don't. I know a guy who did it and ended up in the ER with a blood pressure so low they had to hook him up to a machine that looked like it belonged in a spaceship. He said it was 'worth it.' He also still hasn't had sex since.
Bottom line: there's no miracle. Just trade-offs. Pick your poison. But please, for the love of God, don't buy some 'premium PE booster' off Instagram that says 'clinically proven by a guy named Steve in Thailand.' Steve doesn't know what serotonin is. He sells CBD gummies with glitter in them.
Paul Maxben
November 2, 2025 AT 11:59lol Poxet is just a fancy name for a drug that makes you feel like you got hit by a bus then had your dick wrapped in duct tape. i tried it. got dizzy. threw up. still came in 45 seconds. the real problem? men are too lazy to learn how to control themselves so they just pop pills like candy. wake up. your body is not broken. you just need discipline. also the 'natural supplements' are scams. ginseng? please. i ate a whole root once. tasted like dirt. still came fast. the only thing that works? stop watching porn. that's the real cause. your brain is rewired. fix that first. then maybe you won't need drugs.
Molly Britt
November 4, 2025 AT 01:31Did you know that the FDA doesn’t regulate these 'topical sprays'? That’s why they’re sold over the counter. But here’s the thing-they’re all secretly laced with low-dose dapoxetine. They just don’t list it. Why? So they can avoid clinical trials. I’ve seen the leaked emails. Big Pharma doesn’t want you to know you can get the same effect from a $12 spray as a $90 prescription. They’re milking you. Wake up.
Nick Cd
November 5, 2025 AT 22:53Guys I’m not gonna lie I took Poxet and then went on a date and my heart started racing like I was being chased by a bear and my vision went all blurry and I thought I was dying and I had to call 911 and the paramedic looked at me and said 'did you take that blue pill?' and I said 'yes' and he said 'you idiot' and I said 'but it was supposed to help me last longer' and he said 'you’re supposed to take it like a normal human being not like you’re trying to win a marathon in your pants' and now I’m scared to ever touch another pill again and I think the government is hiding the truth about serotonin and they’re using it to control men’s orgasms and I saw a documentary on YouTube where a guy said the CIA invented PE to keep men distracted from world domination and I don’t know what to believe anymore
Patricia Roberts
November 6, 2025 AT 09:17Oh wow. So the solution to premature ejaculation is… to pay someone to give you a chemical to delay your body’s natural response? How very 2024. Next they’ll sell us pills to stop blinking too fast or to prevent involuntary smiling during funerals. At this point, I just want to know who’s making money off our shame. Not you, honey. Not you.
Adrian Clark
November 7, 2025 AT 19:27Let’s be real. Poxet is just the pharmaceutical industry’s way of turning a biological quirk into a chronic condition. You’re not broken. You’re just a guy who gets excited. The real problem? Society told you that lasting longer = being a man. Bullshit. I’ve had sex with women who said they’d rather have a guy who comes fast and is emotionally present than some robot who lasts 15 minutes but looks like he’s doing taxes during intercourse. Maybe the answer isn’t more drugs. Maybe it’s less pressure.
Rob Giuffria
November 8, 2025 AT 19:59Every time I see someone talking about 'natural remedies' for PE, I think of the guy who tried to cure his diabetes with lemon juice and yoga. You can’t out-herb a physiological response. Serotonin isn’t a spirit animal you can summon with ginger tea. The fact that people believe L-arginine fixes PE proves we’ve entered the post-truth era of male insecurity. We’d rather swallow snake oil than admit we need to talk to a therapist. The real cure? Vulnerability. The rest is just noise.
Barnabas Lautenschlage
November 9, 2025 AT 08:09I’ve read through this entire post and the comments, and I think the most important takeaway is that there’s no one-size-fits-all solution. Dapoxetine works for some, behavioral techniques for others, and topical treatments for a third group. The key is matching the approach to your personal physiology, lifestyle, and psychological state. I’ve seen men who tried everything-pills, sprays, supplements-and only found relief after combining cognitive behavioral therapy with pelvic floor exercises. It’s not glamorous, but it’s sustainable. Also, the fact that you’re researching this at all means you’re already ahead of most people. Don’t rush. Don’t panic. Just gather data about your own body and respond accordingly.
Ryan Argante
November 10, 2025 AT 23:06While I appreciate the clinical breakdown, I’d like to offer a slightly more structured perspective. The data presented is accurate and well-sourced. However, I would emphasize that treatment efficacy should be evaluated not only by IELT metrics but also by patient-reported outcomes: satisfaction, anxiety reduction, and relational harmony. Behavioral interventions, despite requiring more time, demonstrate superior long-term retention and lower relapse rates. Furthermore, the integration of partner communication into any treatment plan significantly increases success probability. I encourage readers to treat this not as a 'fix,' but as a holistic improvement process. Your health is worth the investment.
Jeanette Case
November 10, 2025 AT 23:46Okay but can we just talk about how weird it is that we’re all so obsessed with timing? Like, why does it matter if you last 2 minutes or 8? What if the real problem is that we’re not connecting? I tried Poxet. It worked. But I felt like a robot. Then I started talking to my partner before sex-like, actually asking how she wanted to feel-and suddenly I didn’t care how long I lasted. We laughed. We messed up. We tried things. And guess what? I came later anyway. Maybe the answer isn’t a pill… it’s a conversation 💬❤️
Leonard Buttons
November 11, 2025 AT 03:18Just a heads up-some of those 'OTC sprays' on Amazon have benzocaine levels that are way over safe limits. I checked the ingredients on a few. One had 20% when the max is 5%. You can get methemoglobinemia from that. Don't be dumb. If you're gonna use a spray, get one from a pharmacy, not a random seller with 4 stars and 3 reviews. And if you're thinking about supplements? Stick to ones with USP or NSF certification. Otherwise you're just gambling with your liver.
Lenard Trevino
November 12, 2025 AT 20:19Wait-so you’re telling me that the guy who said 'just talk to your partner' actually has a point? I mean… I’ve been married 12 years and I’ve never once said 'hey, how do you want me to feel during sex?' I just assumed she wanted me to last longer. Turns out she just wanted me to stop pretending I’m not nervous. We had a 20-minute talk last night. I cried. She cried. We didn’t have sex. But we held hands for an hour. And I didn’t even think about PE once. Maybe the real drug isn’t dapoxetine… it’s honesty.