You've probably seen the name Cefixime on a prescription bottle or a pharmacy website and wondered, "Is this the right antibiotic for me?" Whether you’ve just been diagnosed with a bacterial infection or you’re researching options for a loved one, you need clear answers fast. This guide cuts through the medical jargon, explains exactly what Cefixime is, how to use it correctly, what to watch out for, and where to source it without breaking the bank.
TL;DR - Quick Takeaways
- Cefixime is a third‑generation oral cephalosporin antibiotic used for throat, ear, sinus, urinary and certain gastrointestinal infections.
- Typical adult dose is 400mg once daily or 200mg twice daily for 5-10 days, depending on infection severity.
- Common side effects: mild stomach upset, diarrhea, rash. Serious reactions are rare but include severe allergic responses.
- Never mix Cefixime with certain antacids or live vaccines; always tell your doctor about other meds.
- In Australia you need a prescription; compare pharmacy prices and online services for the best deal.
What Is Cefixime and When Is It Prescribed?
Cefixime belongs to the cephalosporin family, which works by disrupting bacterial cell wall formation. Think of it like a tiny hammer that cracks the wall, causing the bug to burst open. Because it’s a third‑generation drug, it’s stronger against many Gram‑negative bacteria while still covering some Gram‑positive strains.
Doctors typically reach for Cefixime when they need an oral option that can tackle:
- Acute bacterial sinusitis
- Pharyngitis (strep throat) not responding to penicillin
- Uncomplicated urinary tract infections
- Travel‑related diarrhoea caused by Escherichia coli (especially in regions with high resistance)
- Ear infections (otitis media) in children over six months
It’s not a first‑line choice for pneumonia or complicated abdominal infections-those usually need IV therapy. If you’ve been handed a Cefixime script, it means your doctor believes the infection is likely susceptible and you can manage it at home.
How to Take Cefixime: Dosage, Administration, and Practical Tips
Getting the dosage right is the most important step to beat the infection and prevent resistance. Below is a simple cheat‑sheet for the most common scenarios:
Patient Group | Indication | Typical Dose | Duration |
---|---|---|---|
Adults | Sinusitis, Pharyngitis, UTI | 400mg once daily OR 200mg twice daily | 5-10 days |
Children (6mo-12yr) | Otitis media, Uncomplicated UTI | 8mg/kg once daily (max 400mg) | 5-7 days |
Elderly (>65yr) | Any indicated infection | Same as adult; monitor kidney function | 5-10 days |
Key administration pointers:
- Take with a full glass of water. This helps the tablet dissolve and reduces stomach irritation.
- Food does not significantly affect absorption, so you can take it with or without meals-pick whatever fits your routine.
- If you’re on an antacid containing aluminium or magnesium, space the doses at least 2hours apart. Those minerals can bind the drug and cut its effectiveness.
- Never double up if you miss a dose. Take the missed tablet as soon as you remember, unless it’s almost time for the next dose-then skip the missed one.
- Finish the entire course, even if you feel better after a few days. Stopping early lets bacteria survive and become resistant.
For children who can’t swallow tablets, the liquid suspension (100mg/5ml) is widely available. Shake well before each use to keep the dose accurate.

Safety First: Side Effects, Interactions, and When to Call the Doctor
Most people tolerate Cefixime just fine. The mild side effects you might notice within the first couple of days include:
- Upset stomach or mild nausea
- Loose stools or occasional diarrhea
- Transient headache
- Rash that looks like tiny red bumps
If any of these linger beyond a week, or if they become severe, talk to your pharmacist or doctor.
Serious, though rare, reactions demand immediate medical attention:
- Difficulty breathing, swelling of lips or tongue (signs of anaphylaxis)
- Severe skin reaction - blistering, peeling, or a fever with a rash (possible Stevens‑Johnson syndrome)
- Persistent watery diarrhea that looks like you’re “running to the bathroom” for more than three days - could be C.difficile infection.
Drug interaction checklist:
- Antacids with aluminium or magnesium - take them at least 2hours apart.
- Warfarin - Cefixime may slightly increase INR; monitor blood clotting.
- Live vaccines (e.g., yellow fever) - antibiotics can blunt the immune response; schedule vaccines at least 2weeks before starting Cefixime.
- Other antibiotics - avoid stacking unless directed; overlapping spectra can cause unnecessary side effects.
Pregnant or breastfeeding women should only use Cefixime if the benefits outweigh potential risks, as classified by the FDA as Category B (no proven risk in animal studies, but limited human data).
Getting Cefixime in Australia: Prescription Rules, Prices, and Smart Buying Tips
In Australia, Cefixime is a Schedule4 (prescription‑only) medicine. That means you’ll need a valid script from a GP or a qualified prescriber. Here’s how to navigate the process smoothly:
- Telehealth options: Many clinics now offer video consults. You can get an electronic prescription sent directly to your pharmacy.
- Pharmacy pick‑up vs. delivery: Major chains (Chemist Warehouse, Priceline) often have the generic 400mg tablets in stock. Prices range from $15 to $25 for a 10‑day supply.
- Online pharmacies: Sites like Pharmacyonline.com.au compare prices and sometimes offer a 5% discount for first‑time users. Make sure the site requires a prescription and displays a physical Australian address.
- Bulk buying: If you’re prone to recurrent infections, ask your doctor about a repeat prescription. Buying a 30‑day pack can shave $5-$8 off the unit cost.
Don’t be tempted by “no‑prescription” offers from overseas retailers. Not only is it illegal, but the product may be counterfeit, sub‑potent, or unsafe.
Lastly, keep a copy of your prescription (digital or paper) for at least six months. Some insurers require it for medication claims, and it helps if you need a refill.
Mini‑FAQ - Your Follow‑Up Questions Answered
- Can I take Cefixime with food? Yes, food doesn’t affect its absorption, so you can take it with meals for comfort.
- What if I forget a dose? Take it as soon as you remember unless it’s almost time for the next dose; then skip the missed one and continue.
- Is Cefixime safe for children? Yes, for kids over six months when dosed by weight. The liquid suspension is easier for young ones.
- Will it work for viral infections like the common cold? No. Cefixime attacks bacteria, not viruses, and misuse can breed resistance.
- How long does it stay in my system? The drug’s half‑life is about 3-4hours, but therapeutic effects last until the course ends.

Next Steps - Put the Knowledge into Action
If you’ve just received a Cefixime script, start by confirming the dosage instructions with your pharmacist. Set a daily alarm on your phone to help you remember the dose, and keep a glass of water handy.
If you’re still unsure whether Cefixime is the right antibiotic for your condition, schedule a brief telehealth consult. Bring a list of your current meds, any allergies, and a short summary of your symptoms.
Finally, compare a couple of local pharmacy prices before you head out. A quick online lookup can save you a few bucks and ensure you get the genuine product.
Armed with this guide, you can take Cefixime confidently, avoid common pitfalls, and get back to feeling your best in just a few days.